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Zika virus testing is performed in the United States at CDC and four state health department laboratories, and CDC is working to expand laboratory diagnostic testing to additional states.

Health care providers should contact their state or local health department to facilitate testing.

What are the implications for public health practice?

The best way to prevent Zika virus infection is to avoid mosquito bites by avoiding exposure and eliminating mosquito breeding areas.

There is no commercially available test for Zika virus.

Zika virus infection should be considered in patients with acute onset of fever, maculopapular rash, arthralgia, or conjunctivitis, who traveled to areas with ongoing transmission in the 2 weeks preceding illness onset.

Because dengue and chikungunya virus infections share a similar geographic distribution with Zika virus and symptoms of infection are similar, patients with suspected Zika virus infections also should be evaluated and managed for possible dengue or chikungunya virus infection (9,10).

Aedes albopictus mosquitoes also might transmit the virus. albopictus mosquitoes are found throughout much of the Americas, including parts of the United States, and also transmit dengue and chikungunya viruses.

In addition to mosquito-to-human transmission, Zika virus infections have been documented through intrauterine transmission resulting in congenital infection, intrapartum transmission from a viremic mother to her newborn, sexual transmission, blood transfusion, and laboratory exposure (5).

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